Aspects of greening peptide chemistry within the pharmaceutical manufacturing industry
In 2016 a critical need for development of greener alternatives within the peptide manufacturing processes was identified. The move towards achieving this has started on several levels within the industry. The awareness of the need and requests for greener alternatives have reached the peptide manufacturers, who, in response, are working on expansion of the greener processing options. […]
In 2016 a critical need for development of greener alternatives within the peptide manufacturing processes was identified. The move towards achieving this has started on several levels within the
industry. The awareness of the need and requests for greener alternatives have reached the peptide manufacturers, who, in response, are working on expansion of the greener processing options. Exchange of harmful solvents to greener alternatives, reduction of overall need for solvent, elimination of processing steps for smarter processing and recycling are all achievable and encompassed by the 12 principles of green chemistry. However, a single effort is not enough, many contributions are necessary to achieve the goal of overall greener manufacturing processes without compromising the product quality and still being conscious of the manufacturing costs.
Jon H. Rasmussen, Global Director Development
Oligonucleotides & Peptides, Chimica Oggi, Chemistry Today, March/April 2019