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ReGreen SPPS: enabling circular chemistry in environmentally sensible solid-phase peptide synthesis
15 Oct 2019 - Aiming at greener, scalable methods for cost-efficient peptide synthesis a solid-phase peptide synthesis (SPPS) protocol adhering to the principles of circular chemistry[…]
Read moreA Holistic Quality Control Strategy for Peptide Active Pharmaceutical Ingredients (APIs)
14 Sep 2019 - The goal of consistently achieving critical quality attributes (CQAs) for synthetic peptide active pharmaceutical ingredients (APIs) may be challenging owing to the complexity of the manufacturing process and the large number of potential sources of variability. […]
Read moreEconomic and environmental factors affecting the sustainability of peptide therapeutic manufacturing
14 Sep 2019 - The outlook for peptide therapeutic drugs is bright. The range of medical indications is expanding and the rate at which peptide therapeutic drugs are being approved is increasing.[…]
Read morePoster: Benzylthiols as scavengers in TFA cleavages of peptide resins
29 Jun 2019 - Poster from 26th APS Monterey, Jun 2019 […]
Read more2D green SPPS: green solvents for on-resin removal of acid sensitive protecting groups and lactamization
15 May 2019 - Aiming at greener synthesis of complex peptides we report that conventional one-dimensional (1D) green solid-phase peptide synthesis (SPPS) is elevated to a two-dimensional (2D) concept […]
Read moreAspects of greening peptide chemistry within the pharmaceutical manufacturing industry
30 Apr 2019 - In 2016 a critical need for development of greener alternatives within the peptide manufacturing processes was identified. The move towards achieving this has started on several levels within the industry. The awareness of the need and requests for greener alternatives have reached the peptide manufacturers, who, in response, are working on expansion of the greener processing options. […]
Read morePanel discussion on peptides
30 Apr 2019 - With Robert Hagopian, Director, Business Development […]
Read moreNeedle-to-needle’: Manufacturing NeoAntigen peptides
28 Feb 2019 - Trishul Shah of PolyPeptide Laboratories looks at the prospects for individualised peptide therapeutics* […]
Read moreAdvanced SPPS
28 Feb 2019 - Olivier Ludemann-Hombourger of PolyPeptide Laboratories and N. Petitjean of Ypso-Facto look at the challenge of large-scale peptide synthesis on solid supports*[…]
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