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Green Chemistry Articles of Interest to the Pharmaceutical Industry

22 Feb 2024 - Org. Process Res. Dev. 2024, 28, 652–660 Ashley, M. A.; Aukland, M. H.; Bryan, M. C.; Cismesia, M. A.; Dutschei, T.; Engl, O. D.; Engl, P. […]

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Green Chemistry Articles of Interest to the Pharmaceutical Industry

13 Sep 2023 - Org. Process Res. Dev. 2023, 27, 1858–1867 Ashley, M. A.; Aukland, M. H.; Bryan, M. C.; Cismesia, M. A.; Engl, O. D.; Engl, P. S.; Garcia, […]

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Quality Assessment and Minimizing Racemization, Precipitation, and Radical-Induced Side Reactions by TBEC/Oxyma Couplings in an Environmentally Sensible Solvent

23 Jun 2023 - Elevating 1-tert-Butyl-3-ethylcarbodiimide (TBEC) as a Reagent for Sustainable Peptide Synthesis: Quality Assessment and Minimizing Racemization, Precipitation, and Radical-Induced Side Reactions by TBEC/Oxyma Couplings in an Environmentally […]

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Trending topics at PolyPeptide

1 Jun 2023 - We are proud to share some of the recent recorded presentations from our experts at TIDES USA 2023: “Raw material control strategy” Eran Benjamin, Global Director […]

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Assessment of Sulfur Impurities in GMP-Grade Diisopropylcarbodiimide and Their Impact on Coupling Reagent-Induced Side Reactions in Peptide Synthesis

4 May 2023 -   Jan Pawlas and Jon H. Rasmussen Abstract Diisopropylcarbodiimide (DIC) constitutes one of the most widely used coupling reagents for amide bond formation in peptide synthesis. […]

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Green Chemistry Articles of Interest to the Pharmaceutical Industry

4 Apr 2023 - Bryan, M. C.; Dalton, C.; Díaz-Rodríguez, A.; Doerfler, J.; Engl, O. D.; Molina, A. G.; Harawa, V.; Kelly, C. B.; Li, W.; Munday, R. H.; Pawlas, […]

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Developing the Toolbox for Sustainable Peptide Manufacturing

24 Mar 2023 - The need for sustainable manufacturing practices is a major challenge for the worldwide industry, and the pharma world is increasingly engaged in this important green transformation. […]

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Overcoming Oligonucleotide Manufacturing Challenges

24 Mar 2023 - The Oligonucleotide CMO industry faces a number of challenges – Demand out pacing capacity for manufacturing, available expertise, high solvent and waste usage to name a […]

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Chemical strategies in extending half-lives of therapeutic peptides

24 Mar 2023 - Therapeutic peptides have been proven to be very effective in treating critical human diseases. Their number on the pharmaceutical market has significantly increased over the past […]

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