TIDES USA

Venue:
Manchester Grand Hyatt San Diego, USA
Booth #506
Presentations:
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Process Intensification in Large Scale Peptide Manufacturing, Olivier Ludemann-Hombourger, PhD The growing demand for peptide-based therapies, particularly for metabolic diseases, has created significant challenges in large-scale production. One of the primary hurdles is meeting the high-volume needs of the pharmaceutical market while maintaining product quality, sustainability, and cost-effectiveness. PolyPeptide, a CDMO leader in peptide manufacturing, is addressing these challenges with an innovative approach focused on process intensification. This strategy aims to rethink and optimize the production platform, integrating advanced technologies that enhance productivity, reduce costs, and increase sustainability. By leveraging cutting-edge solutions, PolyPeptide is improving the scalability of peptide manufacturing while maintaining the stringent standards required by the pharmaceutical industry. This novel approach not only supports the growing market demand but also ensures the delivery of high-quality therapies. PolyPeptide’s position at the forefront of peptide production innovation is key to supporting the next generation of treatments for metabolic diseases and beyond. , 2:10pm |
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Challenges and Strategies in Managing Peptide Aggregation, El Djouhar Rekaï, PhD Peptide aggregation remains a significant challenge in pharmaceutical development impacting solubility, stability and therapeutic efficacy of peptide-based drugs. It can be driven by numerous factors and conditions complicating the manufacturing and storage of those molecules. This presentation explores the current understanding of peptide aggregation mechanisms. Key challenges in identifying and mitigating aggregation during manufacturing processes will be discussed. Case studies on complex long peptide sequences prone to aggregation will be shared. , 9:30am |
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Co-Chairs’ Remarks: GLP-1 and Beyond: Peptide Therapeutics for Diabetes and Obesity/Oral Peptide and Novel Peptide Delivery Technologies, Trishul Shah, M.S. , 1:55pm |
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