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Sustainable, cost-efficient manufacturing of therapeutic peptides using chemo-enzymatic peptide synthesis (CEPS)
22 Nov 2019 - Using a large scale biocatalytic manufacture of the antidiabetic exenatide as an example, we report that chemo-enzymatic peptide synthesis (CEPS) constitutes an efficient method for sustainable manufacturing of therapeutic peptides. […]
Read moreReGreen SPPS: enabling circular chemistry in environmentally sensible solid-phase peptide synthesis
15 Oct 2019 - Aiming at greener, scalable methods for cost-efficient peptide synthesis a solid-phase peptide synthesis (SPPS) protocol adhering to the principles of circular chemistry[…]
Read more2D green SPPS: green solvents for on-resin removal of acid sensitive protecting groups and lactamization
15 May 2019 - Aiming at greener synthesis of complex peptides we report that conventional one-dimensional (1D) green solid-phase peptide synthesis (SPPS) is elevated to a two-dimensional (2D) concept […]
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